ERCC1 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | UV20, DNA REPAIR DEFECT UV-20 OF CHINESE HAMSTER OVARY CELLS, COMPLEMENTATION OF EXCISION-REPAIR, COMPLEMENTING DEFECTIVE IN CHINESE HAMSTER, excision repair cross-complementing 1 isoform 1 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P07992 | | Иммуноген | Synthesized peptide derived from human ERCC1. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | | Примечание | Isoform 1:Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4.<br/><br/>Kan-Tai Hsia, Development, Jan 2003, 130: 369.<br/>Jim Selfridge, Nucleic Acids Res., Nov 2001, 29: 4541 - 4550.<br/>Cha-Kyung Youn, Cancer Res., Jul 2004, 64: 4849 - 4857.<br/>Teresa A. Motycka, J. Biol. Chem., Apr 2004, 279: 13634 - 13639.<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Epigenetics and Nuclear Signaling,Cancer | | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using ERCC1 antibody.
 | Western blot analysis of extracts from NIH/3T3 cells, using ERCC1 antibody.
 | Western blot analysis of extracts from Hela cells (Lane 2), using ERCC1 antiobdy. The lane on the left is treated with synthesized peptide.
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Наименование: ERCC1 Antibody.