Объем | 100 мкл |
Синонимы | ER, ESR, ESR1, ESTR, ESTRA |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P03372 |
Иммуноген | Peptide sequence around aa.102~106 (S-V-S-P-S) derived from Human Estrogen Receptor-a. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:200 |
Примечание | Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.<br/><br/>Medunjanin S, et al. (2005). J Biol Chem.80 (38):33006-33014.<br/>Dutertre M, et al. (2003). Mol Endocrinol.17 (7): 1296-1314.<br/>Chen D, et al. (2000). Mol Cell.6 (1): 127-137.<br/>Rogatsky I, et al. (1999). J Biol Chem.274 (32): 22296-22302.<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
Области исследований | Epigenetics and Nuclear Signaling,Neuroscience,Cancer,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from MCF-7
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Estrogen Receptor-a(Ab-104) Antibody(left) or the same antibody preincubated with blocking peptide(right).
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