Объем | 100 мкл |
Синонимы | EWS oncogene, Ewing sarcoma breakpoint region 1 protein, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q01844 |
Иммуноген | Synthesized peptide derived from internal of human EWSR1. |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Might normally function as a transcriptionnal repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.<br/><br/>Delattre O., Nature 359:162-165(1992).<br/>Plougastel B., Genomics 18:609-615(1993).<br/>Zucman-Rossi J., Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases.<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Epigenetics and Nuclear Signaling,Cancer,Tags & Cell Markers |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HeLa cells, Jurkat cells and K562 cells, using EWSR1 antibody.
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