Объем | 100 мкл |
Синонимы | Cytochrome P450 2A6, EC 1.14.14.1, CYPIIA6, Coumarin 7-hydroxylase, P450 IIA3 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P11509 |
Иммуноген | Synthesized peptide derived from N-terminal of human Cytochrome P450 2A6. |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1,4-cineole 2-exo-monooxygenase. Possesses low phenacetin O-deethylation activity.<br/><br/>Miles J.S., ic Acids Res. 17:2907-2917(1989).<br/>Yamano S., Biochemistry 29:1322-1329(1990).<br/>Saito S., J. Hum. Genet. 48:249-270(2003).<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Cancer,Cardiovascular,Metabolism,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from Jurkat cells, using Cytochrome P450 2A6 antibody.
|
| |