| Объем | 100 мкл |
| Синонимы | CK1-epsilon, CKI-epsilon, CKIe, CSNK1E, Casein kinase I |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P49674 |
| Иммуноген | Synthesized peptide derived from internal of human CKI-ε. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC, IF,WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 |
| Примечание | Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. In balance with PP1, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phospohorylation. Controls PER1 and PER2 nuclear transport and degradation. Inhibits cytokine-induced granuloytic differentiation.<br/><br/>Fish K.J., J. Biol. Chem. 270:14875-14883(1995).<br/>Okamura A., Blood 103:2997-3004(2004).<br/>Collins J.E., Genome Biol. 5:RESEARCH84.1-RESEARCH84.11(2004). |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry analysis of paraffin-embedded human placenta tissue using CKI-? antibody.
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Immunofluorescence analysis of HeLa cells, using CKI-? antibody.
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Western blot analysis of extracts from LOVO cells, using CKI-? antibody.
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Western blot analysis of extracts from HuvEc cells (Lane 2), JK cells (Lane 3) and cos-7 cells (Lane 4), using CKI-? antiobdy antiobdy. The lane on the left is treated with synthesized peptide.
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Наименование: CSNK1E Antibody.