CST3 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | Cystatin C | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P01034 | | Иммуноген | Synthetic peptide of human CST3 | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA, WB, IHC,ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:50-1:200 | | Примечание | The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antigen affinity purification | | Области исследований | Cardiovascular,Cell biology,Tags & Cell Markers,Stem cells | | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using CSB-PA592744(CST3 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ?200)
 | Gel: 12%SDS-PAGE, Lysate: 40 ?g, Lane: Human fetal brain tissue, Primary antibody: CSB-PA592744(CST3 Antibody) at dilution 1/2400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
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Наименование: CST3 Antibody.