Объем | 100 мкл |
Синонимы | Cadherin-associated protein, Alpha E-catenin, NY-REN-13 antigen |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P35221 |
Иммуноген | Peptide sequence around aa. 639~643 (D-D-S-D-F) derived from Human a-catenin. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB,WB:1:500-1:1000 |
Примечание | Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. May play a crucial role in cell differentiation.<br/><br/>Hwang, S.G. et al. (2005) J. Biol. Chem. 280, 12758-12765<br/>Drees, F. et al. (2005) Cell 123, 903-915.<br/>Yamada, S. et al. (2005) Cell 123, 889-901.<br/>Kobielak, A. and Fuchs, E. (2004) Nat. Rev. Mol. Cell Biol. 5, 614-625.<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
Области исследований | Cancer,Signal transduction,Stem cells |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from Hela and 293 cells using a-catenin(Ab-641) antibody.
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