DAB1 (Ab-232) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | Disabled homolog 1 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | O75553 | | Иммуноген | Peptide sequence around aa.230~234 (G-V-Y-D-V) derived from Human Dab1. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, IHC,IHC:1:50-1:100 | | Примечание | The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.<br/><br/>Kelian Chen, et,al. (2003) J. Cell Sci , 117: 4527 - 4536.<br/>Vera Strasser, et,al. (2004) Mol. Cell. Biol , 24: 1378 - 1386.<br/>Izhar Ben-Shlomo, et,al. (2003) Sci. STKE , 2003: 9.<br/>H. M. Kim, et,al. (2002) PNAS , 99: 4020.<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | | Области исследований | Neuroscience,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Dab1(Ab-232) Antibody(left) or the same antibody preincubated with blocking peptide(right).
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Наименование: DAB1 (Ab-232) Antibody.