Объем | 100 мкл |
Синонимы | dynactin 4 (p62) |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q9UJW0 |
Иммуноген | Fusion protein of human DCTN4 |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, IHC,ELISA:1:2000-1:5000, IHC:1:50-1:200 |
Примечание | Dynactin is a multisubunit complex and a required cofactor for most, or all, of the cellular processes powered by the microtubule-based motor cytoplasmic dynein . Dynactin contains a short actin-related protein 1 (Arp1) filament with capZ at the barbed end and p62 at the pointed end . The p62 subunit is an integral component of 20 S dynactin with a highly conserved cysteine-rich motif that interacts directly with Arp1. Dynactin p62 has a punctate cytoplasmic distribution as well as centrosomal distribution typical of dynactin . In addition, Dynactin p62 is distributed in the nucleus at very high expression levels . Due to the structural composition of dynactin, the p62 subunit is implicated in Arp1 pointed-end binding and in linking dynein and dynactin to the cortical cytoskeleton. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA561781(DCTN4 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ?200)
![](http://www.cusabio.cn/images/antibody/shgo/IHC/CSB-PA561781-P.jpg) |
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA561781(DCTN4 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ?200)
![](http://www.cusabio.cn/images/antibody/shgo/IHC/CSB-PA561781-1-P.jpg) |
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