CYP2C8 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | Cytochrome P450 2C8, EC 1.14.14.1, CYPIIC8, P450 form 1, P450 MP-12/MP-20 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P10632 | Иммуноген | Synthesized peptide derived from internal of human Cytochrome P450 2C8. | Источник | Rabbit | Видовая специфичность | Human | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | Примечание | Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. In the epoxidation of arachidonic acid it generates only 14,15- and 11,12-cis-epoxyeicosatrienoic acids. It is the principal enzyme responsible for the metabolism the anti-cancer drug paclitaxel (taxol).<br/><br/>Romkes M., Biochemistry 30:3247-3255(1991).<br/>Ged C., Biochim. Biophys. Acta 1088:433-435(1991).<br/>Zeldin D.C., Arch. Biochem. Biophys. 322:76-86(1995).<br/> <br/> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Области исследований | Cancer,Cardiovascular,Metabolism,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from HuvEc cells, using Cytochrome P450 2C8 antiobdy.
| Immunohistochemistry analysis of paraffin-embedded human testis tissue, using Cytochrome P450 2C8 antibody.
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