CYP2E1 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | cytochrome P450, family 2, subfamily E, polypeptide 1 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P05181 | Иммуноген | Fusion protein of human CYP2E1 | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB, IHC,ELISA:1:1000-1:2000, WB:1:500-1:2000, IHC:1:25-1:100 | Примечание | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Cancer,Cardiovascular,Metabolism,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA186108(CYP2E1 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: ?200)
| Gel: 8%SDS-PAGE, Lysate: 40 ?g, Lane: Mouse liver tissue, Primary antibody: CSB-PA186108(CYP2E1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
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