Объем | 100 мкл |
Синонимы | ATP/GTP-binding protein-like 4, CBPC6, CCP6, cytosolic carboxypeptidase 6, EC 3.4.17.- |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q5VU57 |
Иммуноген | Synthesized peptide derived from internal of human CBCP6. |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5 By similarity.<br/><br/>Ota T., Nat. Genet. 36:40-45(2004).<br/>Gregory S.G., Nature 441:315-321(2006).<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Cell biology,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HeLa cells, Jurkat cells and A549 cells, using CBCP6 antibody.
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