| Объем | 100 мкл |
| Синонимы | F-box only protein 2, FBXO2, FBX2 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9UK22 |
| Иммуноген | Recombinant Human F-box only protein 2 protein (1-296AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, IHC, Recommended dilution: IHC:1:20-1:200 |
| Примечание | Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type (By similarity). |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen Affinity Purified |
| Абревеатура | F-box only protein 2 |
| Области исследований | Cell biology |
| Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA892326ESR1HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human glioma using CSB-PA892326ESR1HU at dilution of 1:100
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Наименование: FBXO2 Antibody.