| Объем | 100 мкг |
| Синонимы | Cytotoxin 4 (CTX-4M) (CTX4) (Cardiotoxin A4) (CTX A4) (Cardiotoxin analog IV) (CTX IV) |
| Клональность | Polyclonal Antibody |
| Организм | Naja atra |
| uniprot | P01443 |
| Иммуноген | Recombinant Naja atra Cytotoxin 4 protein (22-81AA) |
| Источник | Rabbit |
| Видовая специфичность | Naja atra |
| Применение | ELISA |
| Примечание | Basic protein that bind to cell membrane and depolarizes cardiomyocytes. This cytotoxin also shows lytic activities, but 2-fold more important than that of CTX-A2. It binds to the integrin alpha-V/beta-3 with a moderate affinity. Inhibits protein kinase C. It may interact with sulfatides in the cell membrane, which induces pore formation and cell internalization and is responsible for cytotoxicity in cardiomyocytes. It also may target the mitochondrial membrane and induces mitochondrial swelling and fragmentation. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Области исследований | Others |
| Ссылка на страницу на сайте производителя | ссылка |
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Наименование: Cytotoxin 4 Antibody.