Объем | 100 мкл |
Синонимы | mRNA-decapping enzyme 1A, EC 3.-.-.-, Transcription factor SMIF, Smad4-interacting transcriptional co-activator, DCP1A |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q9NPI6 |
Иммуноген | Synthesized peptide derived from internal of human DCP1A. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1.<br/><br/>Lykke-Andersen J., Mol. Cell. Biol. 22:8114-8121(2002).<br/>Bai R.-Y., Nat. Cell Biol. 4:181-190(2002).<br/>Ota T., Nat. Genet. 36:40-45(2004).<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Epigenetics and Nuclear Signaling |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from Jurkat cells, using DCP1A antibody.
![](http://www.cusabio.cn/images/cb/CSB-PA111070-WB-1.jpg) |
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