DCTN1 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | dynactin 1 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q14203 | Иммуноген | Fusion protein of human DCTN1 | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB, IHC,ELISA:1:2000-1:10000, WB:1:200-1:1000, IHC:1:100-1:300 | Примечание | This gene encodes the largest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. Dynactin is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Neuroscience,Cell biology,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA038642(DCTN1 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ?200)
| The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CSB-PA038642(DCTN1 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ?200)
| Gel: 6%SDS-PAGE, Lysate: 40 ?g, Lane 1-2: 293T cells, human fetal brain tissue, Primary antibody: CSB-PA038642(DCTN1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
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