| Объем | 100 мкг |
| Синонимы | DIS3-like exonuclease 1 (EC 3.1.13.-), DIS3L, DIS3L1 KIAA1955 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q8TF46 |
| Иммуноген | Recombinant Human DIS3-like exonuclease 1 protein (1-300AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC, Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200 |
| Примечание | Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Области исследований | Epigenetics and Nuclear Signaling, Cell biology |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: DIS3L antibody at 6µg/ml
Lane 1: Hela whole cell lysate
Lane 2: HepG2 whole cell lysate
Lane 3: MCF-7 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 121, 106, 87, 112 kDa
Observed band size: 121 kDa
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Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA823476LA01HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA823476LA01HU at dilution of 1:100
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Наименование: DIS3L Antibody.