FOS AntibodyСпецификация| Объем | 100 мкл | | Синонимы | p55, AP-1, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P01100 | | Иммуноген | Peptide sequence around aa.28~32( S-Y-Y-H-S) derived from Human C-Fos. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB,WB:1:500-1:1000 | | Примечание | Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation.<br/><br/>Okazaki K., Sagata N.EMBO J. 14:5048-5059(1995)<br/>Zhang Y., Feng X.H., Derynck R.Nature 394:909-913(1998) <br/>Bossis G., Malnou C.E., Farras R. Mol. Cell. Biol. 25:6964-6979(2005) | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | | Области исследований | Epigenetics and Nuclear Signaling,Neuroscience,Cancer | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from A549, Hela and 3T3 cells using C-Fos Antibody.
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Наименование: FOS Antibody.