Объем | 100 мкл |
Синонимы | Docking protein 4, Downstream of tyrosine kinase 4, DOK4, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q8TEW6 |
Иммуноген | Synthesized peptide derived from internal of human DOK4. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway By similarity. Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells.<br/><br/>Favre C., Genes Immun. 4:40-45(2003).<br/>Cai D., J. Biol. Chem. 278:25323-25330(2003).<br/>Loftus B.J., Genomics 60:295-308(1999).<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Neuroscience,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from 293 cells and mouse lung cells, using DOK4 antibody.
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