Объем | 100 мкл |
Синонимы | growth arrest and DNA-damage-inducible, beta |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | O75293 |
Иммуноген | Fusion protein of human GADD45B |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, IHC,ELISA:1:2000-1:5000, IHC:1:50-1:200 |
Примечание | This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Epigenetics and Nuclear Signaling,Cancer,Cell biology,Immunology,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA212749(GADD45B Antibody) at dilution 1/30. (Original magnification: ?200)
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The image is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA212749(GADD45B Antibody) at dilution 1/30. (Original magnification: ?200)
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