Объем | 100 мкл |
Синонимы | Transcription factor E2F2, E2F-2, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q14209 |
Иммуноген | Synthesized peptide derived from internal of human E2F2. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from g1 to s phase. E2F2 binds specifically to RB1 in a cell-cycle dependent manner.<br/><br/>Ivey-Hoyle M., Mol. Cell. Biol. 13:7802-7812(1993).<br/>Gregory S.G., Nature 441:315-321(2006).<br/>Novy M., Mol. Biol. Cell 16:2181-2190(2005).<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Epigenetics and Nuclear Signaling |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HepG2 cells, K562 cells and COLO205 cells, using E2F2 antibody.
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