Объем | 100 мкл |
Синонимы | AT591, CMT1D, CMT4E, DKFZp686J1957, early growth response 2 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P11161 |
Иммуноген | Synthesized peptide derived from C-terminal of human EGR2. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4. E3 SUMO-protein ligase helping SUMO1 conjugation to its coregulators NAB1 and NAB2, whose sumoylation down-regulates EGR2 own transcriptional activity.<br/><br/>Joseph L.J., Proc. Natl. Acad. Sci. U.S.A. 85:7164-7168(1988).<br/>Warner L.E., Nat. Genet. 18:382-384(1998).<br/>Bechtel S., BMC Genomics 8:399-399(2007).<br/><br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Epigenetics and Nuclear Signaling,Neuroscience |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from K562 cells, using EGR2 antibody.
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