| Объем | 100 мкл |
| Синонимы | DKFZp686L18198, eIF-2-beta, EIF2, EIF2B, EIF2beta |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P20042 |
| Иммуноген | Synthesized peptide derived from N-terminal of human eIF2B. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.<br/><br/>Pathak V.K., Cell 54:633-639(1988).<br/>Deloukas P., Nature 414:865-871(2001).<br/>Olsen J.V., Cell 127:635-648(2006).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from K562 cells, using eIF2B (Ab-67) antibody.
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Western blot analysis of extracts from JK cells (Lane 2), using eIF2B (Ab-67) antiobdy. The lane on the left is treated with systhesized peptide.
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Наименование: EIF2S2 (Ab-67) Antibody.