EIF4G2 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | Eukaryotic translation initiation factor 4 gamma 2 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P78344 | Иммуноген | Synthetic peptide of human EIF4G2 | Источник | Rabbit | Видовая специфичность | Human, Mouse | Применение | ELISA, WB,ELISA:1:2000-1:5000, WB:1:500-1:2000 | Примечание | Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3, eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Epigenetics and Nuclear Signaling,Cancer,Cell biology | Ссылка на страницу на сайте производителя | ссылка | Gel: 6%SDS-PAGE,Lysate: 40 ?g,Lane 1-2: Hela cells, HepG2 cells,Primary antibody: CSB-PA063947(EIF4G2 Antibody) at dilution 1/500 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 1 minute
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