Объем | 100 мкл |
Синонимы | RNA polymerase II elongation factor ELL, RNA polymerase II elongation factor ELL, ELL, C19orf17, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P55199 |
Иммуноген | Synthesized peptide derived from internal of human ELL. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. ELL also plays an early role before its assembly into in the SEC complex by stabilizing RNA polymerase II recruitment/initiation and entry into the pause site. Required to stabilize the pre-initiation complex and early elongation.<br/><br/>Thirman M.J., Proc. Natl. Acad. Sci. U.S.A. 91:12110-12114(1994).<br/>Simone F., Blood 98:201-209(2001).<br/>Kong S.E., Proc. Natl. Acad. Sci. U.S.A. 102:10094-10098(2005).<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Epigenetics and Nuclear Signaling,Cancer |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from Jurkat cells and HeLa cells, using ELL antibody.
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