| Объем | 50 мкл |
| Синонимы | ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor), ELF4, ELFR MEF |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q99607 |
| Иммуноген | Recombinant Human ETS-related transcription factor Elf-4 protein (1-200AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, IHC, Recommended dilution: IHC:1:20-1:200 |
| Примечание | Transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. Transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. Acts synergistically with RUNX1 to transactivate the IL3 promoter (By similarity). Also transactivates the PRF1 promoter in natural killer (NK) cells. Plays a role in the development and function of NK and NK T-cells and in innate immunity. Controls the proliferation and homing of CD8+ T-cells via the Kruppel-like factors KLF4 and KLF2 (By similarity). Controls cell senescence in a p53-dependent manner. Can also promote cellular transformation through inhibition of the p16 pathway. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen Affinity Purified |
| Области исследований | Epigenetics and Nuclear Signaling, Cancer |
| Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA857453ESR2HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human prostate tissue using CSB-PA857453ESR2HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA857453ESR2HU at dilution of 1:100
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Наименование: ELF4 Antibody.