| Объем | 50 мкл |
| Синонимы | Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11), EPHB4, HTK MYK1 TYRO11 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P54760 |
| Иммуноген | Recombinant Human Ephrin type-B receptor 4 protein (300-540AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC, Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 |
| Примечание | Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation form EFNB2-expressing cells. Plays also a role in postnatal blood vessel remodeling, morphogenesis and permeability and is thus important in the context of tumor angiogenesis. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen Affinity Purified |
| Абревеатура | Ephrin type-B receptor 4 |
| Области исследований | Neuroscience, Cardiovascular, Stem cells |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: EPHB4 antibody at 2.71µg/ml
Lane 1: A549 whole cell lysate
Lane 2: 293T whole cell lysate
Lane 3: Hela whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 109, 56, 34, 46 kDa
Observed band size: 109 kDa
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Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA007732ESR1HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA007732ESR1HU at dilution of 1:100
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Наименование: EPHB4 Antibody.