| Объем | 100 мкл |
| Синонимы | Erythropoietin receptor, EPO-R, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P19235 |
| Иммуноген | Synthesized peptide derived from Internal of human Epo-R. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.<br/><br/>Winkelmann J.C., Blood 76:24-30(1990) [PubMed: 2163695].<br/>Jones S.S.,Blood 76:31-35(1990) [PubMed: 2163696].<br/>Noguchi C.T., Blood 78:2548-2556(1991) [PubMed: 1668606].<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Cardiovascular,Immunology,Signal transduction,Stem cells |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from JurKat cells, using Epo-R (Ab-426) antibody.
 |
| | |
Наименование: EPOR (Ab-426) Antibody.