GRM4 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | Metabotropic glutamate receptor 4, mGluR4, GPRC1D, MGLUR4, GRM4 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q14833 | Иммуноген | Synthesized peptide derived from human GluR4. | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | Примечание | G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.<br/><br/>Susana Santos Correia, J. Biol. Chem., Feb 2003, 278: 6307 - 6313.<br/>Maxim Mokin, J Neurophysiol, Jan 2006, 95: 215 - 224.<br/>Maxim Mokin, J Neurophysiol, Jan 2006, 95: 215 - 224.<br/>Peyman Golshani, PNAS, Mar 2001, 98: 4172.<br/> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Области исследований | Neuroscience,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemical analysis of paraffin-embedded human brain tissue using GluR4 antibody.
 | Western blot analysis of extracts from 293 cells, untreated or treated with Forskolin (40nM, 30mins), using GluR4 antibody.
 | Western blot analysis of extracts from JK cells (Lane 2), using mGluR4 antiobdy. The lane on the left is treated with synthesized peptide.
 | | |
Информация для заказа |