ERBB2 (Ab-1248) AntibodyСпецификацияОбъем | 100 мкл | Синонимы | C-erbB-2, ErbB2, | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P04626 | Иммуноген | Peptide sequence around aa. 1246~1250 (P-E-Y-L-G) derived from Human HER2. | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB, IHC, IF,WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200 | Примечание | Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Not activated by EGF, TGF-a and amphiregulin.<br/><br/>Ramsauer VP, et al. (2003)J Biol Chem, 278(32): 30142-7.<br/>Jepson S, et al. (2002)Oncogene, 21(49): 7524-32.<br/>Ren Z, et al. (2002)J Biol Chem, 277(41): 38486-93.<br/>Eppenberger-Castori S, et al. (2001)J Clin Oncol, 19(3): 645-56.<br/> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | Области исследований | Cancer,Tags & Cell Markers,Immunology,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from MCF and SKOV3 cells using HER2(Ab-1248) Antibody.
| Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using HER2(Ab-1248) Antibody(left) or the same antibody preincubated with blocking peptide(right).
| Immunofluorescence staining of methanol-fixed MCF7 cells using HER2(Ab-1248) Antibody.
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