Объем | 100 мкл |
Синонимы | TFIIH basal transcription factor complex p44 subunit, Basic transcription factor 2 44 kDa subunit, BTF2-p44, General transcription factor IIH polypeptide 2, GTF2H2 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q13888 |
Иммуноген | Synthesized peptide derived from N-terminal of human TF2H2. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. The N-terminus interacts with and regulates XPD whereas an intact C-terminus is required for a successful escape of RNAP II form the promoter.<br/><br/>Humbert S., EMBO J. 13:2393-2398(1994).<br/>The MGC Project Team, Genome Res. 14:2121-2127(2004).<br/>van der Steege G., Eur. J. Hum. Genet. 3:87-95(1995).<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Epigenetics and Nuclear Signaling |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from COLO205 cells, using TF2H2 antibody.
![](http://www.cusabio.cn/images/cb/CSB-PA714270-WB-1.jpg) |
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