Объем | 100 мкл |
Синонимы | Cytovillin, EZRI, p81, VIL2, Villin 2 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P15311 |
Иммуноген | Synthesized non-phosphopeptide derived from human Ezrin around the phosphorylation site of tyrosine 478 (P-V-Y(p)-E-P). |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.<br/><br/>Gould K.L., EMBO J. 8:4133-4142(1989).<br/>Turunen O., J. Biol. Chem. 264:16727-16732(1989).<br/>Mungall A.J., Nature 425:805-811(2003).<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Cancer,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from K562 cells, using Ezrin (Ab-478) antibody.
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Western blot analysis of extracts from COS7 cells (Lane 2), using Ezrin (Ab-478) antiobdy. The lane on the left is treated with synthesized peptide.
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