| Объем | 50 мкл |
| Синонимы | epidermal growth factor receptor pathway substrate 15-like 1 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9UBC2 |
| Иммуноген | Fusion protein of human EPS15L1 |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC,ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
| Примечание | Epidermal growth factor receptor substrate 15-like 1 is a protein that in humans is encoded by the EPS15L1gene. Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR), internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. Interacts with EPS15, AGFG1/HRB and AGFG2/HRBL. Associates with the clathrin-associated adapter protein complex 2 (AP-2) By similarity. Interacts with FCHO1. Interacts with FCHO2. Interacts (via EH domains) with DAB2. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen affinity purification |
| Области исследований | Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA524180(EPS15L1 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ?200)
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The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA524180(EPS15L1 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ?200)
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Gel: 8%SDS-PAGE, Lysate: 40 ?g, Lane 1-4: Hela cells, PC3 cells, 231 cells, 293T cells, Primary antibody: CSB-PA524180(EPS15L1 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
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Наименование: EPS15L1 Antibody.