Объем | 100 мкл |
Синонимы | DNA excision repair protein ERCC-5, DNA-repair protein complementing XP-G cells, ERCC5, XPGC, Xeroderma pigmentosum group G complementing protein |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P28715 |
Иммуноген | Synthesized peptide derived from internal of human ERCC5. |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | <p>Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. Makes the 3'incision in DNA nucleotide excision repair (NER). Acts as a cofactor for a DNA glycosylase that removes oxidized pyrimidines from DNA. May also be involved in transcription-coupled repair of this kind of damage, in transcription by RNA polymerase II, and perhaps in other processes too.<br /><br />Scherly D., Nature 363:182-185(1993).<br />Shiomi T., Mutat. Res. 314:167-175(1994).<br />Macinnes M.A., Mol. Cell. Biol. 13:6393-6402(1993).</p> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Epigenetics and Nuclear Signaling |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from colo cells, using ERCC5 antibody.
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