HAT1 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | Histone acetyltransferase 1, Histone acetyltransferase type B catalytic subunit, EC 2.3.1.48, HAT1, | Клональность | Polyclonal Antibody | Организм | Human | uniprot | O14929 | Иммуноген | Synthesized peptide derived from Internal of human HAT. | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB,WB:1:500-1:3000 | Примечание | <p>Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. May be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes. May play a role in DNA repair in response to free radical damage.<br /><br />Claudia J. Schroder-Adams, Bulletin of Canadian Petroleum Geology, Sep 1997, 45: 356 - 376. <br />Pil-Hoon Park, Am J Physiol Gastrointest Liver Physiol, Dec 2005, 289: G1124 - G1136. <br />Claudia J. Schroeder-Adams, Palaios, Aug 1998, 13: 361 - 375. <br />L. J. Patric</p> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Области исследований | Epigenetics and Nuclear Signaling | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from K562 cells, using HAT antibody.
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