Объем | 100 мкл |
Синонимы | Protein HEXIM1, Hexamethylene bis-acetamide-inducible protein 1, Cardiac lineage protein 1, Estrogen down-regulated gene 1 protein, Menage a quatre protein 1 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | O94992 |
Иммуноген | Synthesized peptide derived from Internal of human HES7. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB, IF,WB:1:500-1:3000, IF:1:100-1:500 |
Примечание | Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity.<br/><br/>Kusuhara M., Biomed. Res. 20:273-279(1999).<br/>Wittmann B.M., Cancer Res. 63:5151-5158(2003).<br/>Ouchida R., Genes Cells 8:95-107(2003).<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Epigenetics and Nuclear Signaling,Cardiovascular |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from NIH-3T3 cells, using HES7 antibody.
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Immunofluorescence analysis of HeLa cells, using HES7 antibody.
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