| Объем | 50 мкг |
| Синонимы | Exonuclease 1 (hExo1) (EC 3.1.-.-) (Exonuclease I) (hExoI), EXO1, EXOI HEX1 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9UQ84 |
| Иммуноген | Recombinant Human Exonuclease 1 protein (301-600AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC, Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 |
| Примечание | 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5' or 3' to the mismatch. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin genes. Essential for male and female meiosis. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Области исследований | Epigenetics and Nuclear Signaling |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: EXO1 antibody at 10µg/ml
Lane 1: Hela whole cell lysate
Lane 2: 293T whole cell lysate
Lane 3: A549 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 95, 90 kDa
Observed band size: 95 kDa
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Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA007876LA01HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human stomach tissue using CSB-PA007876LA01HU at dilution of 1:100
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Наименование: EXO1 Antibody.