FAM3B AntibodyСпецификацияОбъем | 50 мкл | Синонимы | family with sequence similarity 3, member B | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P58499 | Иммуноген | Fusion protein of human FAM3B | Источник | Rabbit | Видовая специфичность | Human, Mouse | Применение | ELISA, IHC,ELISA:1:2000-1:5000, IHC:1:50-1:200 | Примечание | FAM3B (family with sequence similarity 3, member B), also known as ORF9, C21orf11 or PANDER, is a 235 amino acid secreted protein that localizes to discrete vesicular and perinuclear structures. Expressed at high levels in pancreas and at lower levels in kidney, colon, testis, prostate and small intestine, FAM3B functions as an islet-specific cytokine that promotes apoptosis and may inhibit Insulin secretion from beta-cells, possibly playing a role in overall pancreatic activity. Human FAM3B shares 78% sequence identity with its mouse counterpart, suggesting a conserved role between species. Three isoforms of FAM3B, designated A, B and C, exist due to alternative splicing events. The gene encoding FAM3B maps to human chromosome 21, which houses approximately 300 genes and comprises nearly 1.5% of the human genome. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Immunology,Metabolism | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA828051(FAM3B Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ?200)
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