FBXO32 AntibodyСпецификацияОбъем | 50 мкл | Синонимы | F-box protein 32 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q969P5 | Иммуноген | Fusion protein of human FBXO32 | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB, IHC,ELISA:1:1000-1:5000, WB:1:200-1:1000, IHC:1:25-1:100 | Примечание | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Cardiovascular,Cell biology,Stem cells | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA996906(FBXO32 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ?200)
| The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA996906(FBXO32 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ?200)
| Gel: 10%SDS-PAGE, Lysate: 40 ?g, Lane 1-2: HT29 cells, human liver cancer tissue, Primary antibody: CSB-PA996906(FBXO32 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes
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