| Объем | 50 мкг |
| Синонимы | Fermitin family homolog 2 (Kindlin-2) (Mitogen-inducible gene 2 protein) (MIG-2) (Pleckstrin homology domain-containing family C member 1) (PH domain-containing family C member 1), FERMT2, KIND2 MIG2 PLEKHC1 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q96AC1 |
| Иммуноген | Recombinant Human Fermitin family homolog 2 protein (155-232AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA |
| Примечание | Scaffolding protein that enhances integrin activation mediated by TLN1 and/or TLN2, but activates integrins only weakly by itself. Binds to membranes enriched in phosphoinositides. Enhances integrin-mediated cell adhesion onto the extracellular matrix and cell spreading, this requires both its ability to interact with integrins and with phospholipid membranes. Required for the assembly of focal adhesions. Participates in the connection between extracellular matrix adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and cell shape modulation. Recruits FBLIM1 to focal adhesions. Plays a role in the TGFB1 and integrin signaling pathways. Stabilizes active CTNNB1 and plays a role in the regulation of transcription mediated by CTNNB1 and TCF7L2/TCF4 and in Wnt signaling. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Biotin |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Абревеатура | Fermitin family homolog 2 |
| Области исследований | Signal transduction, Stem cells |
| Ссылка на страницу на сайте производителя | ссылка |
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Наименование: FERMT2 Antibody, Biotin conjugated.