Объем | 100 мкл |
Синонимы | Corticosteroid 11-beta-dehydrogenase isozyme 1, 11-DH, 11-beta-hydroxysteroid, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P28845 |
Иммуноген | Synthesized peptide derived from N-terminal of human HSD11B1. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 |
Примечание | Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta-hydroxycholesterol By similarity.<br/><br/>Tannin G.M., J. Biol. Chem. 266:16653-16658(1991).<br/>Draper N., J. Clin. Endocrinol. Metab. 87:4984-4990(2002).<br/>Ota T., Nat. Genet. 36:40-45(2004) .<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Cancer,Metabolism,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HuvEc cells, using HSD11B1 antibody.
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Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using HSD11B1 antibody.
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