FHIT AntibodyСпецификацияОбъем | 50 мкл | Синонимы | fragile histidine triad | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P49789 | Иммуноген | Fusion protein of human FHIT | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB, IHC,ELISA:1:1000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 | Примечание | This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Epigenetics and Nuclear Signaling,Cancer | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA288314(FHIT Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ?200)
| Gel: 8+12%SDS-PAGE, Lysate: 30 ?g, Lane 1-2: Mouse brain tissue, human fetal kidney tissue, Primary antibody: CSB-PA288314(FHIT Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
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