Объем | 100 мкл |
Синонимы | Serine protease HTRA2, mitochondrial (EC 3.4.21.108) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine protease 25) (Serine proteinase OMI), HTRA2, OMI PRSS25 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | O43464 |
Иммуноген | Recombinant Human Serine protease HTRA2, mitochondrial protein (334-458AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB, IHC, Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200 |
Примечание | Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen Affinity Purified |
Области исследований | Neuroscience, Cancer, Cell biology, Metabolism |
Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: HTRA2 antibody at 0.9µg/ml
Lane 1: Hela whole cell lysate
Lane 2: U937 whole cell lysate
Lane 3: 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 49, 39, 47, 40 kDa
Observed band size: 39 kDa
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Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA010902ESR2HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA010902ESR2HU at dilution of 1:100
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