Объем | 100 мкл |
Синонимы | Forkhead box protein O4 (Fork head domain transcription factor AFX1), FOXO4, AFX AFX1 MLLT7 |
Клональность | Polyclonal |
Организм | Human |
uniprot | P98177 |
Иммуноген | Recombinant Human Forkhead box protein O4 protein (45-63AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA |
Примечание | Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | FITC |
Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen Affinity Purified |
Абревеатура | Forkhead box protein O4 |
Области исследований | Epigenetics and Nuclear Signaling, Cancer, Cardiovascular, Cell biology, Metabolism |
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