Объем | 100 мкг |
Синонимы | Folylpolyglutamate synthase, mitochondrial (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolylpolyglutamate synthase) (Tetrahydrofolate synthase), FPGS |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q05932 |
Иммуноген | Recombinant Human Folylpolyglutamate synthase, mitochondrial protein (443-546AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB, Recommended dilution: WB:1:500-1:5000 |
Примечание | Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis. Unsubstituted reduced folates are the preferred substrates. Metabolizes methotrexate (MTX) to polyglutamates. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | >95%, Protein G purified |
Абревеатура | Folylpolyglutamate synthase, mitochondrial |
Области исследований | Metabolism, Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western Blot
Positive WB detected in: HepG2 whole cell lysate, MCF-7 whole cell lysate
All lanes: FPGS antibody at 3.2µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 65, 61, 60, 62 kDa
Observed band size: 65 kDa
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