Объем | 100 мкг |
Синонимы | Forkhead box protein L2, FOXL2 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P58012 |
Иммуноген | Recombinant Human Forkhead box protein L2 protein (116-216AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA |
Примечание | Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Is a regulator of CYP19 expression (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity). Is a transcriptional repressor of STAR. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | HRP |
Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | >95%, Protein G purified |
Абревеатура | Forkhead box protein L2 |
Области исследований | Epigenetics and Nuclear Signaling |
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