| Объем | 100 мкл |
| Синонимы | EC 2.7.1.112, EC 2.7.10.2, Nuclear tyrosine protein kinase RAK, Tyrosine-protein kinase FRK, fyn-related kinase |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P42685 |
| Иммуноген | Synthesized peptide derived from internal of human FRK. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB, IHC, IF,WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 |
| Примечание | Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor.<br/><br/>Lee J., Gene 138:247-251(1994).<br/>Cance W.G., Cell Growth Differ. 5:1347-1355(1994).<br/>Zhang Y., Mol. Cell. Proteomics 4:1240-1250(2005).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Cell biology |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from Jurkat cells, using FRK antibody.
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Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using FRK antibody.
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Immunofluorescence analysis of HUVEC cells, using FRK antibody.
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Наименование: FRK Antibody.