GABRB1 (Ab-434) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | GABA(A) receptor, GABA(A)R beta-1, GBRB1, GABA-RB, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P18505 | | Иммуноген | Peptide sequence around aa.432~436 (R-A-S-Q-L) derived from Human GABRB1. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB,WB:1:500-1:1000 | | Примечание | The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding a 4, a 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia.<br/><br/>Collins AL, et al. (2006) Neurogenetics ,7(3):167-174.<br/>Ma DQ, et al. (2005) Am J Hum Genet ,77(3):377-388.<br/>Edenberg HJ, et al. (2004) Am J Hum Genet ,74(4):705-714.<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | | Области исследований | Neuroscience,Cancer,Metabolism,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from PC12 cells using GABRB1(Ab-434) Antibody and the same antibody preincubated with blocking peptide.
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Наименование: GABRB1 (Ab-434) Antibody.