GCH1 AntibodyСпецификация| Объем | 50 мкл | | Синонимы | GTP cyclohydrolase 1 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P30793 | | Иммуноген | Synthetic peptide of human GCH1 | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA, WB, IHC,ELISA:1:1000-1:5000, WB:1:500-1:2000, IHC:1:5-1:20 | | Примечание | This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described, however, not all variants give rise to a functional enzyme. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antigen affinity purification | | Области исследований | Neuroscience,Cancer,Cell biology,Metabolism,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA964562(GCH1 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: ?200)
 | Gel: 12%SDS-PAGE, Lysate: 60 ?g, Lane: Human fetal liver tissue, Primary antibody: CSB-PA964562(GCH1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 15 seconds
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Наименование: GCH1 Antibody.