| Объем | 50 мкл |
| Синонимы | glucokinase (hexokinase 4) |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P35557 |
| Иммуноген | Synthetic peptide of human GCK |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, IHC,ELISA:1:1000-1:2000, IHC:1:10-1:50 |
| Примечание | Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI). |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen affinity purification |
| Области исследований | Cancer,Metabolism,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA594444(GCK Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ?200)
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The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA594444(GCK Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ?200)
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Наименование: GCK Antibody.